| Month | Game | Strat Date | + | Away | Pitcher | Balance | At | Home | Pitcher | Balance |
| September | 1 | 8/29/2025 | BUR | Shane Bieber | 9L | At | CHI | Janson Junk | 4R | |
| September | 2 | 8/30/2025 | BUR | J.P. Sears* | 1L | At | CHI | Randy Vasquez | 2R | |
| September | 3 | 8/31/2025 | BUR | Justin Verlander | 1L | At | CHI | Nick Martinez | 2L | |
| September | 4 | 9/1/2025 | HUC | Pablo Lopez | 3R | At | BUR | Luis Severino | 2R | |
| September | 5 | 9/2/2025 | HUC | Chris Bassitt | 4R | At | BUR | Brady Singer | 4R | |
| September | 6 | 9/3/2025 | HUC | Drew Rasmussen | 3R | At | BUR | Lucas Giolito | 1L | |
| September | OFF | 9/4/2025 | ||||||||
| September | 7 | 9/5/2025 | + | DUB | Ryan Weathers* | 3R | At | BUR | Shane Bieber | 9L |
| September | 8 | 9/6/2025 | + | DUB | Jackson Jobe | 3L | At | BUR | J.P. Sears* | 1L |
| September | 9 | 9/7/2025 | + | DUB | Matthew Liberatore* | 1R | At | BUR | Justin Verlander | 1L |
| September | 10 | 9/8/2025 | + | DUB | Jose Quintana* | 1R | At | BUR | Lucas Giolito | 1L |
| September | 11 | 9/9/2025 | + | DUB | Andrew Abbott* | E | At | BUR | Brady Singer | 4R |
| September | 12 | 9/10/2025 | + | BUR | Luis Severino | 2R | At | CRC | Kevin Gausman | 3L |
| September | 13 | 9/11/2025 | + | BUR | Shane Bieber | 9L | At | CRC | Tanner Bibee | 1L |
| September | 14 | 9/12/2025 | + | BUR | J.P. Sears* | 1L | At | CRC | Sonny Gray | 5L |
| September | 15 | 9/13/2025 | + | BUR | Justin Verlander | 1L | At | CRC | Michael Wacha | 2L |
| September | OFF | 9/14/2025 | ||||||||
| September | 16 | 9/15/2025 | + | BUR | Brady Singer | 4R | At | CUB | Hunter Greene | 1L |
| September | 17 | 9/16/2025 | + | BUR | Luis Severino | 2R | At | CUB | Edward Cabrera | 1R |
| September | 18 | 9/17/2025 | + | BUR | Shane Bieber | 9L | At | CUB | Mackenzie Gore* | 2L |
| September | 19 | 9/18/2025 | + | BUR | J.P. Sears* | 1L | At | CUB | Kodai Senga | 2R |
| September | 20 | 9/19/2025 | + | BUR | Justin Verlander | 1L | At | CUB | Jake Irvin | 4R |
| September | 21 | 9/20/2025 | + | CRC | Garrett Crochet* | 5L | At | BUR | Brady Singer | 4R |
| September | 22 | 9/21/2025 | + | CRC | Kevin Gausman | 3L | At | BUR | Luis Severino | 2R |
| September | 23 | 9/22/2025 | + | CRC | Tanner Bibee | 1L | At | BUR | Bailey Falter* | 1R |
| September | 24 | 9/23/2025 | + | CRC | Sonny Gray | 5L | At | BUR | J.P. Sears* | 1L |
| + Indicates In Division Game | ||||||||||