| Month | Game | Strat Date | + | Away | Pitcher | Balance | At | Home | Pitcher | Balance |
| August | 1 | 8/3/2025 | CRC | Garrett Crochet* | 5L | At | COL | Shawn Armstrong | 9R | |
| August | 2 | 8/4/2025 | CRC | Kevin Gausman | 3L | At | COL | Tarik Skubal* | E | |
| August | 3 | 8/5/2025 | CRC | Tanner Bibee | 1L | At | COL | Tyler Glasnow | E | |
| August | 4 | 8/6/2025 | COL | Freddy Peralta | E | At | TAM | Zack Wheeler | E | |
| August | 5 | 8/7/2025 | COL | Clarke Schmidt | 5R | At | TAM | Hunter Brown | E | |
| August | 6 | 8/8/2025 | COL | Tyler Holton* | 8L | At | TAM | Trevor Rogers* | 1L | |
| August | OFF | 8/9/2025 | ||||||||
| August | 7 | 8/10/2025 | + | VRN | Sandy Alcantara | 1L | At | COL | Tarik Skubal* | E |
| August | 8 | 8/11/2025 | + | VRN | Jacob Misiorowski | 3R | At | COL | Tyler Glasnow | E |
| August | 9 | 8/12/2025 | + | VRN | Patrick Corbin* | 2L | At | COL | Freddy Peralta | E |
| August | 10 | 8/13/2025 | + | VRN | Chase Dollander | 4R | At | COL | Clarke Schmidt | 5R |
| August | 11 | 8/14/2025 | + | VRN | Will Warren | 2R | At | COL | Tyler Holton* | 8L |
| August | 12 | 8/15/2025 | + | COL | Troy Melton | 3R | At | NIM | Jeffrey Springs* | 1L |
| August | 13 | 8/16/2025 | + | COL | Tarik Skubal* | E | At | NIM | Dylan Cease | E |
| August | 14 | 8/17/2025 | + | COL | Tyler Glasnow | E | At | NIM | Matt Boyd* | 3L |
| August | 15 | 8/18/2025 | + | COL | Freddy Peralta | E | At | NIM | Brad Lord | 5R |
| August | OFF | 8/19/2025 | ||||||||
| August | 16 | 8/20/2025 | + | HUC | Joe Ryan | 5R | At | COL | Clarke Schmidt | 5R |
| August | 17 | 8/21/2025 | + | HUC | Clayton Kershaw* | 3R | At | COL | Troy Melton | 3R |
| August | 18 | 8/22/2025 | + | HUC | Drew Rasmussen | 3R | At | COL | Tarik Skubal* | E |
| August | 19 | 8/23/2025 | + | HUC | Chris Bassitt | 4R | At | COL | Tyler Glasnow | E |
| August | 20 | 8/24/2025 | + | HUC | Blake Snell* | 1R | At | COL | Freddy Peralta | E |
| August | 21 | 8/25/2025 | + | COL | Clarke Schmidt | 5R | At | WRK | Max Meyer | 8L |
| August | 22 | 8/26/2025 | + | COL | Troy Melton | 3R | At | WRK | David Festa | 6L |
| August | 23 | 8/27/2025 | + | COL | Tarik Skubal* | E | At | WRK | Cristopher Sanchez* | 4L |
| August | 24 | 8/28/2025 | + | COL | Tyler Glasnow | E | At | WRK | Casey Mize | 1L |
| + Indicates In Division Game | ||||||||||