| Month | Game | Strat Date | + | Away | Pitcher | Balance | At | Home | Pitcher | Balance |
| June | 1 | 6/8/2025 | AAR | Paul Skenes | 2R | At | WRK | Spencer Strider | E | |
| June | 2 | 6/9/2025 | AAR | Gavin Williams | 3L | At | WRK | Casey Mize | 1L | |
| June | 3 | 6/10/2025 | AAR | Slade Cecconi | 3L | At | WRK | Luis Ortiz | 2R | |
| June | 4 | 6/11/2025 | WRK | Cristopher Sanchez* | 4L | At | DUB | Zebby Matthews | 7R | |
| June | 5 | 6/12/2025 | WRK | Michael McGreevy | 9R | At | DUB | Mitch Keller | 4R | |
| June | 6 | 6/13/2025 | WRK | Spencer Strider | E | At | DUB | David Peterson* | 4L | |
| June | OFF | 6/14/2025 | ||||||||
| June | 7 | 6/15/2025 | + | WRK | Luis Ortiz | 2R | At | COL | Tyler Holton* | 8L |
| June | 8 | 6/16/2025 | + | WRK | Cristopher Sanchez* | 4L | At | COL | Tyler Glasnow | E |
| June | 9 | 6/17/2025 | + | WRK | Michael McGreevy | 9R | At | COL | Brandon Woodruff | 4L |
| June | 10 | 6/18/2025 | + | WRK | Casey Mize | 1L | At | COL | Tarik Skubal* | E |
| June | 11 | 6/19/2025 | + | WRK | Spencer Strider | E | At | COL | Freddy Peralta | E |
| June | 12 | 6/20/2025 | + | VRN | Yusei Kikuchi* | 2L | At | WRK | Luis Ortiz | 2R |
| June | 13 | 6/21/2025 | + | VRN | Chase Dollander | 4R | At | WRK | Cristopher Sanchez* | 4L |
| June | 14 | 6/22/2025 | + | VRN | Sandy Alcantara | 1L | At | WRK | Michael McGreevy | 9R |
| June | 15 | 6/23/2025 | + | VRN | Erick Fedde | 7R | At | WRK | Casey Mize | 1L |
| June | OFF | 6/24/2025 | ||||||||
| June | 16 | 6/25/2025 | + | HUC | Chris Bassitt | 4R | At | WRK | Luis Ortiz | 2R |
| June | 17 | 6/26/2025 | + | HUC | Joe Ryan | 5R | At | WRK | Cristopher Sanchez* | 4L |
| June | 18 | 6/27/2025 | + | HUC | Blake Snell* | 1R | At | WRK | Michael McGreevy | 9R |
| June | 19 | 6/28/2025 | + | HUC | Drew Rasmussen | 3R | At | WRK | Casey Mize | 1L |
| June | 20 | 6/29/2025 | + | HUC | Pablo Lopez | 3R | At | WRK | Spencer Strider | E |
| June | 21 | 6/30/2025 | + | WRK | Luis Ortiz | 2R | At | VRN | Yusei Kikuchi* | 2L |
| June | 22 | 7/1/2025 | + | WRK | Cristopher Sanchez* | 4L | At | VRN | Chase Dollander | 4R |
| June | 23 | 7/2/2025 | + | WRK | Michael McGreevy | 9R | At | VRN | Sandy Alcantara | 1L |
| June | 24 | 7/3/2025 | + | WRK | Casey Mize | 1L | At | VRN | Erick Fedde | 7R |
| + Indicates In Division Game | ||||||||||