| Month | Game | Strat Date | + | Away | Pitcher | Balance | At | Home | Pitcher | Balance |
| March | 1 | 3/27/2025 | COL | Emmet Sheehan | 2L | At | SRD | Kyle Freeland* | 3L | |
| March | 2 | 3/28/2025 | COL | Tarik Skubal* | E | At | SRD | Robbie Ray* | 3L | |
| March | 3 | 3/29/2025 | COL | J.T. Ginn | 9R | At | SRD | Chris Sale* | 3L | |
| March | OFF | 3/30/2025 | ||||||||
| March | 4 | 3/31/2025 | SRD | Chris Paddack | E | At | BUR | Lucas Giolito | 1L | |
| March | 5 | 4/1/2025 | SRD | Yu Darvish | 5R | At | BUR | Bailey Falter* | 1R | |
| March | 6 | 4/2/2025 | SRD | Taj Bradley | 1R | At | BUR | Brady Singer | 4R | |
| March | 7 | 4/3/2025 | AAR | Gavin Williams | 3L | At | SRD | Kyle Freeland* | 3L | |
| March | 8 | 4/4/2025 | AAR | Paul Skenes | 2R | At | SRD | Robbie Ray* | 3L | |
| March | 9 | 4/5/2025 | AAR | Slade Cecconi | 3L | At | SRD | Chris Sale* | 3L | |
| March | 10 | 4/6/2025 | SRD | Chris Paddack | E | At | HUC | Drew Rasmussen | 3R | |
| March | 11 | 4/7/2025 | SRD | Yu Darvish | 5R | At | HUC | Clayton Kershaw* | 3R | |
| March | 12 | 4/8/2025 | SRD | Taj Bradley | 1R | At | HUC | Chris Bassitt | 4R | |
| March | OFF | 4/9/2025 | ||||||||
| March | 13 | 4/10/2025 | CRC | Garrett Crochet* | 5L | At | SRD | Kyle Freeland* | 3L | |
| March | 14 | 4/11/2025 | CRC | Kevin Gausman | 3L | At | SRD | Robbie Ray* | 3L | |
| March | 15 | 4/12/2025 | CRC | Tanner Bibee | 1L | At | SRD | Chris Sale* | 3L | |
| March | 16 | 4/13/2025 | SRD | Chris Paddack | E | At | TEX | Luis Gil | E | |
| March | 17 | 4/14/2025 | SRD | Yu Darvish | 5R | At | TEX | Justin Steele* | 9L | |
| March | 18 | 4/15/2025 | SRD | Taj Bradley | 1R | At | TEX | Nick Lodolo* | 5R | |
| March | 19 | 4/16/2025 | WRK | Cristopher Sanchez* | 4L | At | SRD | Kyle Freeland* | 3L | |
| March | 20 | 4/17/2025 | WRK | Casey Mize | 1L | At | SRD | Robbie Ray* | 3L | |
| March | 21 | 4/18/2025 | WRK | Max Meyer | 8L | At | SRD | Chris Sale* | 3L | |
| + Indicates In Division Game | ||||||||||