| Month | Game | Strat Date | + | Away | Pitcher | Balance | At | Home | Pitcher | Balance |
| April | 1 | 4/19/2024 | COL | Spencer Turnbull | 1L | At | SRD | Taj Bradley | 2R | |
| April | 2 | 4/20/2024 | COL | Tarik Skubal* | 2L | At | SRD | Jordan Hicks | 3R | |
| April | 3 | 4/21/2024 | COL | Erick Fedde | 1R | At | SRD | Robbie Ray* | 1L | |
| April | OFF | 4/22/2024 | ||||||||
| April | 4 | 4/23/2024 | COL | Ranger Suarez* | 3R | At | TEX | Ronel Blanco | 1R | |
| April | 5 | 4/24/2024 | COL | Freddy Peralta | 5L | At | TEX | Hunter Brown | 4L | |
| April | 6 | 4/25/2024 | COL | Spencer Turnbull | 1L | At | TEX | Bryan Woo | 1R | |
| April | 7 | 4/26/2024 | DUB | David Peterson* | 3L | At | COL | Tarik Skubal* | 2L | |
| April | 8 | 4/27/2024 | DUB | Jose Quintana* | 3R | At | COL | Erick Fedde | 1R | |
| April | 9 | 4/28/2024 | DUB | Nestor Cortes* | 6L | At | COL | Ranger Suarez* | 3R | |
| April | 10 | 4/29/2024 | COL | Freddy Peralta | 5L | At | GGG | Jack Flaherty | 4L | |
| April | 11 | 4/30/2024 | COL | Spencer Turnbull | 1L | At | GGG | Michael Lorenzen | 7L | |
| April | 12 | 5/1/2024 | COL | Tarik Skubal* | 2L | At | GGG | Jose Urena | 2L | |
| April | OFF | 5/2/2024 | ||||||||
| April | 13 | 5/3/2024 | NYY | Tanner Houck | 2L | At | COL | Erick Fedde | 1R | |
| April | 14 | 5/4/2024 | NYY | Luis Castillo | 8R | At | COL | Ranger Suarez* | 3R | |
| April | 15 | 5/5/2024 | NYY | Luis Gil | 4R | At | COL | Spencer Turnbull | 1L | |
| April | 16 | 5/6/2024 | COL | Freddy Peralta | 5L | At | DAL | Grayson Rodriguez | 6L | |
| April | 17 | 5/7/2024 | COL | Tarik Skubal* | 2L | At | DAL | Ryne Nelson | 2L | |
| April | 18 | 5/8/2024 | COL | Erick Fedde | 1R | At | DAL | Simeon Woods-Richard | 1L | |
| April | 19 | 5/9/2024 | CHI | Kyle Gibson | 4R | At | COL | Ranger Suarez* | 3R | |
| April | 20 | 5/10/2024 | CHI | Mitch Spence | 2R | At | COL | Spencer Turnbull | 1L | |
| April | 21 | 5/11/2024 | CHI | Yusei Kikuchi* | 1L | At | COL | Freddy Peralta | 5L | |
| + Indicates In Division Game | ||||||||||