| Month | Game | Strat Date | + | Away | Pitcher | Balance | At | Home | Pitcher | Balance |
| September | 1 | 9/9/2020 | COL | Chris Bassitt | 5R | At | BUR | Lance McCullers | 2L | |
| September | 2 | 9/10/2020 | COL | Dylan Bundy | 4R | At | BUR | Justus Sheffield* | 7L | |
| September | 3 | 9/11/2020 | COL | Zac Gallen | 1L | At | BUR | Kyle Freeland* | 3R | |
| September | 4 | 9/12/2020 | AAR | Jacob Degrom | 1R | At | COL | Brandon Woodruff | 1L | |
| September | 5 | 9/13/2020 | AAR | Mike Clevinger | 3R | At | COL | Tyler Mahle | 1L | |
| September | 6 | 9/14/2020 | AAR | Taylor Clarke | 3L | At | COL | Clayton Kershaw* | 2R | |
| September | OFF | 9/15/2020 | ||||||||
| September | 7 | 9/16/2020 | + | COL | Chris Bassitt | 5R | At | HUC | Chris Paddack | 2R |
| September | 8 | 9/17/2020 | + | COL | Dylan Bundy | 4R | At | HUC | Zack Greinke | 8L |
| September | 9 | 9/18/2020 | + | COL | Zac Gallen | 1L | At | HUC | Jorge Lopez | 4R |
| September | 10 | 9/19/2020 | + | COL | Brandon Woodruff | 1L | At | HUC | Austin Voth | 1L |
| September | 11 | 9/20/2020 | + | COL | Clayton Kershaw* | 2R | At | HUC | Daniel Ponce De Leon | 4L |
| September | 12 | 9/21/2020 | + | WRK | Dinelson Lamet | 5L | At | COL | Tyler Mahle | 1L |
| September | 13 | 9/22/2020 | + | WRK | Julio Urias* | 2L | At | COL | Chris Bassitt | 5R |
| September | 14 | 9/23/2020 | + | WRK | Kenta Maeda | 1L | At | COL | Dylan Bundy | 4R |
| September | 15 | 9/24/2020 | + | WRK | Tony Gonsolin | 1R | At | COL | Zac Gallen | 1L |
| September | OFF | 9/25/2020 | ||||||||
| September | 16 | 9/26/2020 | OAK | Dylan Cease | 5R | At | COL | Brandon Woodruff | 1L | |
| September | 17 | 9/27/2020 | OAK | Michael Pineda | 7R | At | COL | Andrew Heaney* | E | |
| September | 18 | 9/28/2020 | OAK | Brad Keller | 3R | At | COL | Tyler Mahle | 1L | |
| September | 19 | 9/29/2020 | CAL | Jon Lester* | 2L | At | COL | Chris Bassitt | 5R | |
| September | 20 | 9/30/2020 | CAL | Michael Wacha | 8L | At | COL | Zac Gallen | 1L | |
| September | 21 | 10/1/2020 | CAL | Jordan Montgomery* | 5L | At | COL | Dylan Bundy | 4R | |
| September | 22 | 10/2/2020 | COL | Andrew Heaney* | E | At | SRD | Randy Dobnak | 3R | |
| September | 23 | 10/3/2020 | COL | Kolby Allard* | 8R | At | SRD | Alec Mills | 9R | |
| September | 24 | 10/4/2020 | COL | Chris Bassitt | 5R | At | SRD | Yu Darvish | 1R | |
| + Indicates In Division Game | ||||||||||