| Month | Game | Strat Date | + | Away | Pitcher | Balance | At | Home | Pitcher | Balance |
| September | 1 | 9/9/2018 | DYE | Eric Lauer* | 7R | At | HUC | Mike Minor* | 1R | |
| September | 2 | 9/10/2018 | DYE | Aaron Nola | E | At | HUC | Wilmer Font | 4R | |
| September | 3 | 9/11/2018 | DYE | Tanner Roark | 3R | At | HUC | Blake Snell* | 9R | |
| September | 4 | 9/12/2018 | HOH | Andrew Cashner | 5L | At | DYE | Jack Flaherty | 1R | |
| September | 5 | 9/13/2018 | HOH | Zach Davies | E | At | DYE | Griffin Canning | 3L | |
| September | 6 | 9/14/2018 | HOH | Felix Pena | 8R | At | DYE | Aaron Nola | E | |
| September | OFF | 9/15/2018 | ||||||||
| September | 7 | 9/16/2018 | + | SRD | Yu Darvish | 2R | At | DYE | Eric Lauer* | 7R |
| September | 8 | 9/17/2018 | + | SRD | Homer Bailey | 5L | At | DYE | Tanner Roark | 3R |
| September | 9 | 9/18/2018 | + | SRD | Adam Plutko | 1R | At | DYE | Aaron Nola | E |
| September | 10 | 9/19/2018 | + | SRD | Dallas Keuchel* | 4L | At | DYE | Yonny Chirinos | 6L |
| September | 11 | 9/20/2018 | + | SRD | Chris Sale* | 3L | At | DYE | Jack Flaherty | 1R |
| September | 12 | 9/21/2018 | + | DYE | Eric Lauer* | 7R | At | GGG | Dustin May | 8R |
| September | 13 | 9/22/2018 | + | DYE | Aaron Nola | E | At | GGG | Wade Miley* | 2L |
| September | 14 | 9/23/2018 | + | DYE | Tanner Roark | 3R | At | GGG | Miles Mikolas | E |
| September | 15 | 9/24/2018 | + | DYE | Yonny Chirinos | 6L | At | GGG | Ivan Nova | E |
| September | OFF | 9/25/2018 | ||||||||
| September | 16 | 9/26/2018 | + | DYE | Aaron Nola | E | At | TAM | Shaun Anderson | 1R |
| September | 17 | 9/27/2018 | + | DYE | Eric Lauer* | 7R | At | TAM | Jose Quintana* | 4L |
| September | 18 | 9/28/2018 | + | DYE | Griffin Canning | 3L | At | TAM | Ariel Jurado | 4L |
| September | 19 | 9/29/2018 | + | DYE | Jack Flaherty | 1R | At | TAM | Nick Pivetta | 1L |
| September | 20 | 9/30/2018 | + | DYE | Aaron Nola | E | At | TAM | Chris Archer | 1L |
| September | 21 | 10/1/2018 | + | GGG | Dustin May | 8R | At | DYE | Tanner Roark | 3R |
| September | 22 | 10/2/2018 | + | GGG | Wade Miley* | 2L | At | DYE | Eric Lauer* | 7R |
| September | 23 | 10/3/2018 | + | GGG | Antonio Senzatela | 2R | At | DYE | Griffin Canning | 3L |
| September | 24 | 10/4/2018 | + | GGG | Ivan Nova | E | At | DYE | Aaron Nola | E |
| + Indicates In Division Game | ||||||||||