| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | CAL | Adalberto Mejia* | At | WRK | Julio Urias* | |
| September | 2 | CAL | Sean Newcomb* | At | WRK | Jimmy Nelson | |
| September | 3 | CAL | Clayton Richard* | At | WRK | Sean Manaea* | |
| September | 4 | WRK | Jaime Garcia* | At | DYE | Ivan Nova | |
| September | 5 | WRK | Kyle Gibson | At | DYE | Daniel Mengden | |
| September | 6 | WRK | Jordan Montgomery* | At | DYE | Aaron Nola | |
| September | OFF | ||||||
| September | 7 | + | VRN | Brandon Woodruff | At | WRK | Jimmy Nelson |
| September | 8 | + | VRN | Sal Romano | At | WRK | Sean Manaea* |
| September | 9 | + | VRN | Robert Gsellman | At | WRK | Jaime Garcia* |
| September | 10 | + | VRN | R.A. Dickey | At | WRK | Kyle Gibson |
| September | 11 | + | VRN | Chad Kuhl | At | WRK | Jordan Montgomery* |
| September | 12 | + | WRK | Jimmy Nelson | At | SYI | Charlie Morton |
| September | 13 | + | WRK | Sean Manaea* | At | SYI | German Marquez |
| September | 14 | + | WRK | Jaime Garcia* | At | SYI | Danny Duffy* |
| September | 15 | + | WRK | Kyle Gibson | At | SYI | Kendall Graveman |
| September | OFF | ||||||
| September | 16 | + | COL | Ervin Santana | At | WRK | Jordan Montgomery* |
| September | 17 | + | COL | Cole Hamels* | At | WRK | Jimmy Nelson |
| September | 18 | + | COL | Mike Montgomery* | At | WRK | Sean Manaea* |
| September | 19 | + | COL | Erasmo Ramirez | At | WRK | Jaime Garcia* |
| September | 20 | + | COL | Junior Guerra | At | WRK | Julio Urias* |
| September | 21 | + | WRK | Jordan Montgomery* | At | HUC | Carlos Carrasco |
| September | 22 | + | WRK | Jimmy Nelson | At | HUC | Jake Arrieta |
| September | 23 | + | WRK | Sean Manaea* | At | HUC | Corey Kluber |
| September | 24 | + | WRK | Jaime Garcia* | At | HUC | Blake Snell* |
| + Indicates In Division Game | |||||||