| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | NYY | Alex Cobb | At | GGG | Reynaldo Lopez | |
| September | 2 | NYY | Jhoulys Chacin | At | GGG | Joe Ross | |
| September | 3 | NYY | Paul Blackburn | At | GGG | Mike Foltynewicz | |
| September | 4 | DUB | Rich Hill* | At | NYY | Carlos Martinez | |
| September | 5 | DUB | Seth Lugo | At | NYY | Trevor Bauer | |
| September | 6 | DUB | Justin Verlander | At | NYY | Alex Cobb | |
| September | OFF | ||||||
| September | 7 | + | OAK | Matt Boyd* | At | NYY | Jhoulys Chacin |
| September | 8 | + | OAK | Jameson Taillon | At | NYY | Paul Blackburn |
| September | 9 | + | OAK | Dan Straily | At | NYY | Carlos Martinez |
| September | 10 | + | OAK | Jharel Cotton | At | NYY | Trevor Bauer |
| September | 11 | + | OAK | Eduardo Rodriguez* | At | NYY | Alex Cobb |
| September | 12 | + | NYY | Jhoulys Chacin | At | HMA | Marcus Stroman |
| September | 13 | + | NYY | Paul Blackburn | At | HMA | Gerrit Cole |
| September | 14 | + | NYY | Carlos Martinez | At | HMA | Marco Estrada |
| September | 15 | + | NYY | Trevor Bauer | At | HMA | Tanner Roark |
| September | OFF | ||||||
| September | 16 | + | NYY | Alex Cobb | At | BZZ | Andrew Cashner |
| September | 17 | + | NYY | Jhoulys Chacin | At | BZZ | Mike Leake |
| September | 18 | + | NYY | Paul Blackburn | At | BZZ | Jason Vargas* |
| September | 19 | + | NYY | Carlos Martinez | At | BZZ | Michael Wacha |
| September | 20 | + | NYY | Trevor Bauer | At | BZZ | Lance Lynn |
| September | 21 | + | HMA | Matt Cain | At | NYY | Alex Cobb |
| September | 22 | + | HMA | Brandon McCarthy | At | NYY | Jhoulys Chacin |
| September | 23 | + | HMA | Gerrit Cole | At | NYY | Paul Blackburn |
| September | 24 | + | HMA | Marco Estrada | At | NYY | Carlos Martinez |
| + Indicates In Division Game | |||||||