| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | CUB | Adam Wainwright | At | VRN | Robert Gsellman | |
| September | 2 | CUB | Julio Teheran | At | VRN | Nate Karns | |
| September | 3 | CUB | Jake Odorizzi | At | VRN | Jakob Junis | |
| September | 4 | HMA | Marco Estrada | At | CUB | Kyle Hendricks | |
| September | 5 | HMA | Tanner Roark | At | CUB | Jeremy Hellickson | |
| September | 6 | HMA | J.A. Happ* | At | CUB | Jon Gray | |
| September | OFF | ||||||
| September | 7 | + | BUR | Drew Pomeranz* | At | CUB | Parker Bridwell |
| September | 8 | + | BUR | Gio Gonzalez* | At | CUB | Adam Wainwright |
| September | 9 | + | BUR | Taijuan Walker | At | CUB | Julio Teheran |
| September | 10 | + | BUR | Lance McCullers | At | CUB | Jake Odorizzi |
| September | 11 | + | BUR | Zack Greinke | At | CUB | Kyle Hendricks |
| September | 12 | + | CUB | Jeremy Hellickson | At | DUB | Jerad Eickhoff |
| September | 13 | + | CUB | Jon Gray | At | DUB | Justin Verlander |
| September | 14 | + | CUB | Parker Bridwell | At | DUB | Rich Hill* |
| September | 15 | + | CUB | Julio Teheran | At | DUB | John Lackey |
| September | OFF | ||||||
| September | 16 | + | CUB | Jake Odorizzi | At | CRC | Matt Harvey |
| September | 17 | + | CUB | Kyle Hendricks | At | CRC | Stephen Strasburg |
| September | 18 | + | CUB | Jeremy Hellickson | At | CRC | Jose Urena |
| September | 19 | + | CUB | Jon Gray | At | CRC | Wade Miley* |
| September | 20 | + | CUB | Parker Bridwell | At | CRC | Sonny Gray |
| September | 21 | + | DUB | John Lackey | At | CUB | Julio Teheran |
| September | 22 | + | DUB | Seth Lugo | At | CUB | Jake Odorizzi |
| September | 23 | + | DUB | Madison Bumgarner* | At | CUB | Jeremy Hellickson |
| September | 24 | + | DUB | Jesse Hahn | At | CUB | Jon Gray |
| + Indicates In Division Game | |||||||