| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| August | 1 | SRD | Francisco Liriano* | At | WRK | Jimmy Nelson | |
| August | 2 | SRD | Rafael Montero | At | WRK | Sean Manaea* | |
| August | 3 | SRD | Yu Darvish | At | WRK | Kyle Gibson | |
| August | 4 | WRK | Jordan Montgomery* | At | OAK | Eduardo Rodriguez* | |
| August | 5 | WRK | Kenta Maeda | At | OAK | Nick Pivetta | |
| August | 6 | WRK | Jimmy Nelson | At | OAK | Jameson Taillon | |
| August | OFF | ||||||
| August | 7 | + | WRK | Sean Manaea* | At | VRN | R.A. Dickey |
| August | 8 | + | WRK | Kyle Gibson | At | VRN | Brandon Woodruff |
| August | 9 | + | WRK | Jordan Montgomery* | At | VRN | Robert Gsellman |
| August | 10 | + | WRK | Kenta Maeda | At | VRN | Chad Kuhl |
| August | 11 | + | WRK | Jimmy Nelson | At | VRN | Jakob Junis |
| August | 12 | + | HUC | Corey Kluber | At | WRK | Sean Manaea* |
| August | 13 | + | HUC | Carlos Carrasco | At | WRK | Kyle Gibson |
| August | 14 | + | HUC | Chris Stratton | At | WRK | Jordan Montgomery* |
| August | 15 | + | HUC | Jon Lester* | At | WRK | Kenta Maeda |
| August | OFF | ||||||
| August | 16 | TAM | Zack Godley | At | WRK | Jimmy Nelson | |
| August | 17 | TAM | Luis Severino | At | WRK | Sean Manaea* | |
| August | 18 | TAM | Jason Hammel | At | WRK | Kyle Gibson | |
| August | 19 | WRK | Jordan Montgomery* | At | CRC | Sonny Gray | |
| August | 20 | WRK | Kenta Maeda | At | CRC | Michael Fulmer | |
| August | 21 | WRK | Jimmy Nelson | At | CRC | Danny Salazar | |
| August | 22 | WRK | Sean Manaea* | At | BZZ | Jason Vargas* | |
| August | 23 | WRK | Kyle Gibson | At | BZZ | Mike Leake | |
| August | 24 | WRK | Jordan Montgomery* | At | BZZ | Michael Wacha | |
| + Indicates In Division Game | |||||||