| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | VRN | Vince Velasquez | At | CRC | Danny Salazar | |
| September | 2 | VRN | Chad Kuhl | At | CRC | Daniel Norris* | |
| September | 3 | VRN | Chris Tillman | At | CRC | Colby Lewis | |
| September | 4 | SRD | Michael Pineda | At | VRN | Aaron Sanchez | |
| September | 5 | SRD | Chris Sale* | At | VRN | Max Scherzer | |
| September | 6 | SRD | Tyler Cravy | At | VRN | David Price* | |
| September | OFF | ||||||
| September | 7 | + | WRK | Mike Foltynewicz | At | VRN | Chad Kuhl |
| September | 8 | + | WRK | Sean Manaea* | At | VRN | Max Scherzer |
| September | 9 | + | WRK | Jimmy Nelson | At | VRN | Aaron Sanchez |
| September | 10 | + | WRK | Ricky Nolasco | At | VRN | Chris Tillman |
| September | 11 | + | WRK | Joe Musgrove | At | VRN | Vince Velasquez |
| September | 12 | + | VRN | Max Scherzer | At | HUC | Jon Lester* |
| September | 13 | + | VRN | Chad Kuhl | At | HUC | Hisashi Iwakuma |
| September | 14 | + | VRN | Aaron Sanchez | At | HUC | Nathan Karns |
| September | 15 | + | VRN | Chris Tillman | At | HUC | Corey Kluber |
| September | OFF | ||||||
| September | 16 | + | VRN | David Price* | At | SYI | Kendall Graveman |
| September | 17 | + | VRN | Vince Velasquez | At | SYI | Adam Conley* |
| September | 18 | + | VRN | Aaron Sanchez | At | SYI | Drew Smyly* |
| September | 19 | + | VRN | Danny Duffy* | At | SYI | James Paxton* |
| September | 20 | + | VRN | David Price* | At | SYI | Hector Santiago* |
| September | 21 | + | HUC | Carlos Carrasco | At | VRN | Chris Tillman |
| September | 22 | + | HUC | Jake Arrieta | At | VRN | Max Scherzer |
| September | 23 | + | HUC | Jon Lester* | At | VRN | Aaron Sanchez |
| September | 24 | + | HUC | Corey Kluber | At | VRN | Vince Velasquez |
| + Indicates In Division Game | |||||||