| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | OAK | Zack Greinke | At | TAM | Jose Quintana* | |
| September | 2 | OAK | Williams Perez | At | TAM | Colin Rea | |
| September | 3 | OAK | Matt Garza | At | TAM | Chris Archer | |
| September | 4 | TAM | Mat Latos | At | COL | Matt Wisler | |
| September | 5 | TAM | Jason Hammel | At | COL | Steven Wright | |
| September | 6 | TAM | Steven Matz* | At | COL | Josh Tomlin | |
| September | OFF | ||||||
| September | 7 | + | TAM | Jose Quintana* | At | GGG | Johnny Cueto |
| September | 8 | + | TAM | Mat Latos | At | GGG | Rick Porcello |
| September | 9 | + | TAM | Jason Hammel | At | GGG | Martin Perez* |
| September | 10 | + | TAM | Chris Archer | At | GGG | Jose Fernandez |
| September | 11 | + | TAM | Kevin Gausman | At | GGG | Johnny Cueto |
| September | 12 | + | DYE | Felix Hernandez | At | TAM | Colin Rea |
| September | 13 | + | DYE | Bartolo Colon | At | TAM | Jose Quintana* |
| September | 14 | + | DYE | Aaron Nola | At | TAM | Jason Hammel |
| September | 15 | + | DYE | Junior Guerra | At | TAM | Chris Archer |
| September | OFF | ||||||
| September | 16 | TAM | Steven Matz* | At | WRK | Mike Foltynewicz | |
| September | 17 | TAM | Jose Quintana* | At | WRK | Jimmy Nelson | |
| September | 18 | TAM | Jason Hammel | At | WRK | Kenta Maeda | |
| September | 19 | TAM | Kevin Gausman | At | AAR | R.A. Dickey | |
| September | 20 | TAM | Colin Rea | At | AAR | Yu Darvish | |
| September | 21 | TAM | Steven Matz* | At | AAR | Jacob Degrom | |
| September | 22 | CAL | Jeremy Hellickson | At | TAM | Chris Archer | |
| September | 23 | CAL | James Shields | At | TAM | Jason Hammel | |
| September | 24 | CAL | Patrick Corbin* | At | TAM | Kevin Gausman | |
| + Indicates In Division Game | |||||||