| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | COL | Josh Tomlin | At | CUB | Brandon Finnegan* | |
| September | 2 | COL | Clayton Kershaw* | At | CUB | Jon Gray | |
| September | 3 | COL | Cole Hamels* | At | CUB | Kyle Hendricks | |
| September | 4 | CUB | Jake Odorizzi | At | OAK | Eduardo Rodriguez* | |
| September | 5 | CUB | Yordano Ventura | At | OAK | Christian Friedrich* | |
| September | 6 | CUB | Miguel Gonzalez | At | OAK | Zack Greinke | |
| September | OFF | ||||||
| September | 7 | + | CRC | Daniel Norris* | At | CUB | Jon Gray |
| September | 8 | + | CRC | Michael Fulmer | At | CUB | Kyle Hendricks |
| September | 9 | + | CRC | Kyle Gibson | At | CUB | Brandon Finnegan* |
| September | 10 | + | CRC | Stephen Strasburg | At | CUB | Julio Teheran |
| September | 11 | + | CRC | Danny Salazar | At | CUB | Miguel Gonzalez |
| September | 12 | + | CUB | Yordano Ventura | At | CAL | Jeremy Hellickson |
| September | 13 | + | CUB | Kyle Hendricks | At | CAL | James Shields |
| September | 14 | + | CUB | Jake Odorizzi | At | CAL | Matt Moore* |
| September | 15 | + | CUB | Julio Teheran | At | CAL | Tyler Duffey |
| September | OFF | ||||||
| September | 16 | + | DUB | Madison Bumgarner* | At | CUB | Miguel Gonzalez |
| September | 17 | + | DUB | John Lackey | At | CUB | Jon Gray |
| September | 18 | + | DUB | Justin Verlander | At | CUB | Yordano Ventura |
| September | 19 | + | DUB | Seth Lugo | At | CUB | Jake Odorizzi |
| September | 20 | + | DUB | Jerad Eickhoff | At | CUB | Julio Teheran |
| September | 21 | + | CUB | Miguel Gonzalez | At | BUR | Zach Davies |
| September | 22 | + | CUB | Brandon Finnegan* | At | BUR | Ian Kennedy |
| September | 23 | + | CUB | Yordano Ventura | At | BUR | Lance McCullers |
| September | 24 | + | CUB | Jake Odorizzi | At | BUR | Wade Miley* |
| + Indicates In Division Game | |||||||