| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | VRN | Vince Velasquez | At | CRC | Danny Salazar | |
| September | 2 | VRN | Chad Kuhl | At | CRC | Daniel Norris* | |
| September | 3 | VRN | Chris Tillman | At | CRC | Colby Lewis | |
| September | 4 | CRC | Anibal Sanchez | At | YDR | Chris Devenski | |
| September | 5 | CRC | Kyle Gibson | At | YDR | Gerrit Cole | |
| September | 6 | CRC | Danny Salazar | At | YDR | J.A. Happ* | |
| September | OFF | ||||||
| September | 7 | + | CRC | Daniel Norris* | At | CUB | Jon Gray |
| September | 8 | + | CRC | Michael Fulmer | At | CUB | Kyle Hendricks |
| September | 9 | + | CRC | Kyle Gibson | At | CUB | Brandon Finnegan* |
| September | 10 | + | CRC | Stephen Strasburg | At | CUB | Julio Teheran |
| September | 11 | + | CRC | Danny Salazar | At | CUB | Miguel Gonzalez |
| September | 12 | + | DUB | Madison Bumgarner* | At | CRC | Daniel Norris* |
| September | 13 | + | DUB | Seth Lugo | At | CRC | Sonny Gray |
| September | 14 | + | DUB | Jerad Eickhoff | At | CRC | Kyle Gibson |
| September | 15 | + | DUB | Justin Verlander | At | CRC | Michael Fulmer |
| September | OFF | ||||||
| September | 16 | + | BUR | Ian Kennedy | At | CRC | Danny Salazar |
| September | 17 | + | BUR | Taijuan Walker | At | CRC | Daniel Norris* |
| September | 18 | + | BUR | Drew Pomeranz* | At | CRC | Anibal Sanchez |
| September | 19 | + | BUR | Wade Miley* | At | CRC | Kyle Gibson |
| September | 20 | + | BUR | Gio Gonzalez* | At | CRC | Stephen Strasburg |
| September | 21 | + | CRC | Danny Salazar | At | DUB | Madison Bumgarner* |
| September | 22 | + | CRC | Daniel Norris* | At | DUB | Justin Verlander |
| September | 23 | + | CRC | Colby Lewis | At | DUB | John Lackey |
| September | 24 | + | CRC | Kyle Gibson | At | DUB | Wade Leblanc* |
| + Indicates In Division Game | |||||||