| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | NYY | Yovani Gallardo | At | SRD | Gavin Floyd | |
| September | 2 | NYY | Chris Sale* | At | SRD | Alexander Colome | |
| September | 3 | NYY | Randall Delgado | At | SRD | Tyler Matzek* | |
| September | 4 | SRD | Jordan Zimmermann | At | CRC | Stephen Strasburg | |
| September | 5 | SRD | Alexander Cobb | At | CRC | Jorge De La Rosa* | |
| September | 6 | SRD | Gavin Floyd | At | CRC | Justin Verlander | |
| September | OFF | ||||||
| September | 7 | + | SRD | Edinson Volquez | At | HUC | Corey Kluber |
| September | 8 | + | SRD | Tyler Matzek* | At | HUC | Hisashi Iwakuma |
| September | 9 | + | SRD | Alexander Colome | At | HUC | Carlos Carrasco |
| September | 10 | + | SRD | Gavin Floyd | At | HUC | Anibal Sanchez |
| September | 11 | + | SRD | Alexander Cobb | At | HUC | Phil Hughes |
| September | 12 | + | COL | T.J. House* | At | SRD | Edinson Volquez |
| September | 13 | + | COL | Chris Young | At | SRD | Tyler Matzek* |
| September | 14 | + | COL | Roenis Elias* | At | SRD | Alexander Colome |
| September | 15 | + | COL | Cliff Lee* | At | SRD | Gavin Floyd |
| September | OFF | ||||||
| September | 16 | SRD | Edinson Volquez | At | CUB | Matt Shoemaker | |
| September | 17 | SRD | Alexander Cobb | At | CUB | Dallas Keuchel* | |
| September | 18 | SRD | Tyler Matzek* | At | CUB | Jeremy Guthrie | |
| September | 19 | SRD | Gavin Floyd | At | YDR | Gerrit Cole | |
| September | 20 | SRD | Alexander Colome | At | YDR | Garrett Richards | |
| September | 21 | SRD | Jordan Zimmermann | At | YDR | Scott Kazmir* | |
| September | 22 | HEN | Tyler Skaggs* | At | SRD | Edinson Volquez | |
| September | 23 | HEN | Nathan Eovaldi | At | SRD | Tyler Matzek* | |
| September | 24 | HEN | Kyle Kendrick | At | SRD | Gavin Floyd | |
| + Indicates In Division Game | |||||||