| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | NIM | Justin Masterson | At | HUC | Phil Hughes | |
| September | 2 | NIM | Todd Redmond | At | HUC | Derek Holland* | |
| September | 3 | NIM | David Phelps | At | HUC | Brandon Beachy | |
| September | 4 | CRC | Justin Verlander | At | NIM | Clayton Kershaw* | |
| September | 5 | CRC | Mat Latos | At | NIM | Zack Greinke | |
| September | 6 | CRC | Mike Minor* | At | NIM | Justin Masterson | |
| September | OFF | ||||||
| September | 7 | + | TAM | Jordan Lyles | At | NIM | Clayton Kershaw* |
| September | 8 | + | TAM | Tyson Ross | At | NIM | Todd Redmond |
| September | 9 | + | TAM | A.J. Griffin | At | NIM | Zack Greinke |
| September | 10 | + | TAM | Jose Quintana* | At | NIM | Justin Masterson |
| September | 11 | + | TAM | Carlos Torres | At | NIM | Clayton Kershaw* |
| September | 12 | + | NIM | David Phelps | At | HEP | Jason Hammel |
| September | 13 | + | NIM | Kevin Slowey | At | HEP | Charlie Morton |
| September | 14 | + | NIM | Zack Greinke | At | HEP | Paul Maholm* |
| September | 15 | + | NIM | Clayton Kershaw* | At | HEP | Jonathon Niese* |
| September | OFF | ||||||
| September | 16 | + | NIM | Justin Masterson | At | YDR | Dillon Gee |
| September | 17 | + | NIM | Todd Redmond | At | YDR | Lance Lynn |
| September | 18 | + | NIM | Clayton Kershaw* | At | YDR | C.J. Wilson* |
| September | 19 | + | NIM | Kevin Slowey | At | YDR | Erik Johnson |
| September | 20 | + | NIM | Samuel Deduno | At | YDR | Bud Norris |
| September | 21 | + | HEP | Jonathon Niese* | At | NIM | Zack Greinke |
| September | 22 | + | HEP | Jason Hammel | At | NIM | Clayton Kershaw* |
| September | 23 | + | HEP | Paul Maholm* | At | NIM | Todd Redmond |
| September | 24 | + | HEP | Jake Peavy | At | NIM | Kevin Slowey |
| + Indicates In Division Game | |||||||