| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | CUB | Kyle Kendrick | At | CHI | Tim Hudson | |
| September | 2 | CUB | Jerome Williams | At | CHI | Scott Feldman | |
| September | 3 | CUB | CC Sabathia* | At | CHI | Jhoulys Chacin | |
| September | 4 | CHI | Tyler Thornburg | At | SYI | Doug Fister | |
| September | 5 | CHI | Jeff Samardzija | At | SYI | Yovani Gallardo | |
| September | 6 | CHI | Matt Cain | At | SYI | Travis Wood* | |
| September | OFF | ||||||
| September | 7 | + | DET | Clay Buchholz | At | CHI | Jhoulys Chacin |
| September | 8 | + | DET | Joe Saunders* | At | CHI | Scott Feldman |
| September | 9 | + | DET | Jose D. Fernandez | At | CHI | Jeff Samardzija |
| September | 10 | + | DET | Johnny Cueto | At | CHI | Tim Hudson |
| September | 11 | + | DET | Homer Bailey | At | CHI | Jhoulys Chacin |
| September | 12 | + | CHI | Matt Cain | At | EGH | Jacob Turner |
| September | 13 | + | CHI | Jeff Samardzija | At | EGH | Tom Milone* |
| September | 14 | + | CHI | Scott Feldman | At | EGH | Jeff Locke* |
| September | 15 | + | CHI | Tim Hudson | At | EGH | Andy Pettitte* |
| September | OFF | ||||||
| September | 16 | + | DYE | Felix Hernandez | At | CHI | Matt Cain |
| September | 17 | + | DYE | Shelby Miller | At | CHI | Jeff Samardzija |
| September | 18 | + | DYE | Patrick Corbin* | At | CHI | Tyler Thornburg |
| September | 19 | + | DYE | Kris Medlen | At | CHI | Scott Feldman |
| September | 20 | + | DYE | Felix Hernandez | At | CHI | Tim Hudson |
| September | 21 | + | CHI | Jhoulys Chacin | At | GOB | David Price* |
| September | 22 | + | CHI | Jeff Samardzija | At | GOB | Aaron Harang |
| September | 23 | + | CHI | Matt Cain | At | GOB | Dan Haren |
| September | 24 | + | CHI | Scott Feldman | At | GOB | Adam Wainwright |
| + Indicates In Division Game | |||||||