| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| August | 1 | SYI | Doug Fister | At | DET | Rick Porcello | |
| August | 2 | SYI | Henderson Alvarez | At | DET | Jered Weaver | |
| August | 3 | SYI | Hyun-Jin Ryu* | At | DET | Jose D. Fernandez | |
| August | 4 | CUB | Kevin Correia | At | SYI | Martin Perez* | |
| August | 5 | CUB | Kyle Kendrick | At | SYI | Yovani Gallardo | |
| August | 6 | CUB | Jerome Williams | At | SYI | Doug Fister | |
| August | OFF | ||||||
| August | 7 | + | CAL | Ervin Santana | At | SYI | Hyun-Jin Ryu* |
| August | 8 | + | CAL | Julio Teheran | At | SYI | Henderson Alvarez |
| August | 9 | + | CAL | Jordan Zimmermann | At | SYI | Martin Perez* |
| August | 10 | + | CAL | Anibal Sanchez | At | SYI | Doug Fister |
| August | 11 | + | CAL | Matt Harvey | At | SYI | Yovani Gallardo |
| August | 12 | + | SYI | Hyun-Jin Ryu* | At | COL | Dan Straily |
| August | 13 | + | SYI | Henderson Alvarez | At | COL | Jarrod Parker |
| August | 14 | + | SYI | Martin Perez* | At | COL | Cole Hamels* |
| August | 15 | + | SYI | Doug Fister | At | COL | Ricky Nolasco |
| August | OFF | ||||||
| August | 16 | + | HUC | Derek Holland* | At | SYI | Hyun-Jin Ryu* |
| August | 17 | + | HUC | Corey Kluber | At | SYI | Henderson Alvarez |
| August | 18 | + | HUC | James Shields | At | SYI | Yovani Gallardo |
| August | 19 | + | HUC | Ian Kennedy | At | SYI | Doug Fister |
| August | 20 | + | HUC | Derek Holland* | At | SYI | Martin Perez* |
| August | 21 | + | SYI | Hyun-Jin Ryu* | At | SRD | Mark Buehrle* |
| August | 22 | + | SYI | Henderson Alvarez | At | SRD | Jeff Francis* |
| August | 23 | + | SYI | Yovani Gallardo | At | SRD | Scott Kazmir* |
| August | 24 | + | SYI | Doug Fister | At | SRD | Jeremy Hellickson |
| + Indicates In Division Game | |||||||