| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| August | 1 | SYI | Doug Fister | At | DET | Rick Porcello | |
| August | 2 | SYI | Henderson Alvarez | At | DET | Jered Weaver | |
| August | 3 | SYI | Hyun-Jin Ryu* | At | DET | Jose D. Fernandez | |
| August | 4 | DET | Homer Bailey | At | NIM | Carlos Villanueva | |
| August | 5 | DET | Joe Saunders* | At | NIM | David Phelps | |
| August | 6 | DET | Bruce Chen* | At | NIM | Justin Masterson | |
| August | OFF | ||||||
| August | 7 | + | CHI | Jhoulys Chacin | At | DET | Rick Porcello |
| August | 8 | + | CHI | Matt Cain | At | DET | Jose D. Fernandez |
| August | 9 | + | CHI | Jeff Samardzija | At | DET | Homer Bailey |
| August | 10 | + | CHI | Tim Hudson | At | DET | Joe Saunders* |
| August | 11 | + | CHI | Jhoulys Chacin | At | DET | Bruce Chen* |
| August | 12 | + | DET | Jered Weaver | At | EGH | Marco Estrada |
| August | 13 | + | DET | Rick Porcello | At | EGH | Jeff Locke* |
| August | 14 | + | DET | Jose D. Fernandez | At | EGH | Andy Pettitte* |
| August | 15 | + | DET | Homer Bailey | At | EGH | Nathan Eovaldi |
| August | OFF | ||||||
| August | 16 | + | DET | Jered Weaver | At | GOB | Adam Wainwright |
| August | 17 | + | DET | Rick Porcello | At | GOB | Hiroki Kuroda |
| August | 18 | + | DET | Jose D. Fernandez | At | GOB | David Price* |
| August | 19 | + | DET | Homer Bailey | At | GOB | Aaron Harang |
| August | 20 | + | DET | Joe Saunders* | At | GOB | Dan Haren |
| August | 21 | + | EGH | Jacob Turner | At | DET | Jered Weaver |
| August | 22 | + | EGH | Marco Estrada | At | DET | Rick Porcello |
| August | 23 | + | EGH | Jeff Locke* | At | DET | Jose D. Fernandez |
| August | 24 | + | EGH | Andy Pettitte* | At | DET | Homer Bailey |
| + Indicates In Division Game | |||||||