| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| August | 1 | COL | Cliff Lee* | At | DYE | Felix Hernandez | |
| August | 2 | COL | Dan Straily | At | DYE | Kris Medlen | |
| August | 3 | COL | Jarrod Parker | At | DYE | Shelby Miller | |
| August | 4 | BUR | Mike Leake | At | COL | Cole Hamels* | |
| August | 5 | BUR | Eric Stults* | At | COL | Ricky Nolasco | |
| August | 6 | BUR | Tim Lincecum | At | COL | Cliff Lee* | |
| August | OFF | ||||||
| August | 7 | + | COL | Dan Straily | At | HUC | Derek Holland* |
| August | 8 | + | COL | Jarrod Parker | At | HUC | James Shields |
| August | 9 | + | COL | Cole Hamels* | At | HUC | Hisashi Iwakuma |
| August | 10 | + | COL | Ricky Nolasco | At | HUC | Ian Kennedy |
| August | 11 | + | COL | Cliff Lee* | At | HUC | Corey Kluber |
| August | 12 | + | SYI | Hyun-Jin Ryu* | At | COL | Dan Straily |
| August | 13 | + | SYI | Henderson Alvarez | At | COL | Jarrod Parker |
| August | 14 | + | SYI | Martin Perez* | At | COL | Cole Hamels* |
| August | 15 | + | SYI | Doug Fister | At | COL | Ricky Nolasco |
| August | OFF | ||||||
| August | 16 | CHI | Scott Feldman | At | COL | Cliff Lee* | |
| August | 17 | CHI | Matt Cain | At | COL | Dan Straily | |
| August | 18 | CHI | Tim Hudson | At | COL | Jarrod Parker | |
| August | 19 | COL | Cole Hamels* | At | YDR | Garrett Richards | |
| August | 20 | COL | Ricky Nolasco | At | YDR | Lance Lynn | |
| August | 21 | COL | Ryan Dempster | At | YDR | C.J. Wilson* | |
| August | 22 | VRN | Yu Darvish | At | COL | Cliff Lee* | |
| August | 23 | VRN | R.A. Dickey | At | COL | Dan Straily | |
| August | 24 | VRN | Bronson Arroyo | At | COL | Jarrod Parker | |
| + Indicates In Division Game | |||||||