| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | TAM | Ivan Nova | At | DYE | Patrick Corbin* | |
| September | 2 | TAM | Luis Mendoza | At | DYE | Felix Hernandez | |
| September | 3 | TAM | Jordan Lyles | At | DYE | Jeff Karstens | |
| September | 4 | CRC | Justin Verlander | At | TAM | Tommy Hanson | |
| September | 5 | CRC | Mike Minor* | At | TAM | Gavin Floyd | |
| September | 6 | CRC | Josh Johnson | At | TAM | Ivan Nova | |
| September | OFF | ||||||
| September | 7 | + | TAM | A.J. Griffin | At | YDR | Trevor Cahill |
| September | 8 | + | TAM | Tommy Hanson | At | YDR | Max Scherzer |
| September | 9 | + | TAM | Gavin Floyd | At | YDR | C.J. Wilson* |
| September | 10 | + | TAM | Ivan Nova | At | YDR | Dillon Gee |
| September | 11 | + | TAM | Luis Mendoza | At | YDR | Chris Young |
| September | 12 | + | DKZ | Lucas Harrell | At | TAM | Brandon McCarthy |
| September | 13 | + | DKZ | Aaron Harang | At | TAM | Tommy Hanson |
| September | 14 | + | DKZ | A.J. Burnett | At | TAM | Gavin Floyd |
| September | 15 | + | DKZ | James McDonald | At | TAM | Ivan Nova |
| September | OFF | ||||||
| September | 16 | VRN | Joe Blanton | At | TAM | Luis Mendoza | |
| September | 17 | VRN | Luke Hochevar | At | TAM | Tommy Hanson | |
| September | 18 | VRN | Yu Darvish | At | TAM | Gavin Floyd | |
| September | 19 | EGH | Matt Harrison* | At | TAM | Ivan Nova | |
| September | 20 | EGH | Tommy Milone* | At | TAM | John Danks* | |
| September | 21 | EGH | Nathan Eovaldi | At | TAM | Luis Mendoza | |
| September | 22 | TAM | Tommy Hanson | At | SRD | Francisco Liriano* | |
| September | 23 | TAM | Gavin Floyd | At | SRD | Jeremy Hellickson | |
| September | 24 | TAM | Ivan Nova | At | SRD | Paul Maholm* | |
| + Indicates In Division Game | |||||||