| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | BUR | Josh Collmenter | At | SRD | Mark Rogers | |
| September | 2 | BUR | Anibal Sanchez | At | SRD | Steve Johnson | |
| September | 3 | BUR | Jon Niese* | At | SRD | Yovani Gallardo | |
| September | 4 | SRD | Alex Cobb | At | GOB | Hiroki Kuroda | |
| September | 5 | SRD | Jeremy Hellickson | At | GOB | David Price* | |
| September | 6 | SRD | Ryan Vogelsong | At | GOB | Edwin Jackson | |
| September | OFF | ||||||
| September | 7 | + | SRD | Mark Buehrle* | At | CVM | Ubaldo Jimenez |
| September | 8 | + | SRD | Yovani Gallardo | At | CVM | Barry Zito* |
| September | 9 | + | SRD | Jeremy Hellickson | At | CVM | J.A. Happ* |
| September | 10 | + | SRD | Ryan Vogelsong | At | CVM | Scott Diamond* |
| September | 11 | + | SRD | Francisco Liriano* | At | CVM | Tommy Hunter |
| September | 12 | + | COL | Madison Bumgarner* | At | SRD | Mark Buehrle* |
| September | 13 | + | COL | Dan Straily | At | SRD | Mark Rogers |
| September | 14 | + | COL | Cliff Lee* | At | SRD | Jeremy Hellickson |
| September | 15 | + | COL | Chad Billingsley | At | SRD | Paul Maholm* |
| September | OFF | ||||||
| September | 16 | SRD | Mark Buehrle* | At | EGH | Nathan Eovaldi | |
| September | 17 | SRD | Francisco Liriano* | At | EGH | Jake Westbrook | |
| September | 18 | SRD | Jeremy Hellickson | At | EGH | Joe Saunders* | |
| September | 19 | SRD | Paul Maholm* | At | VRN | Chris Sale* | |
| September | 20 | SRD | Jair Jurrjens | At | VRN | Bronson Arroyo | |
| September | 21 | SRD | Mark Buehrle* | At | VRN | Joe Blanton | |
| September | 22 | TAM | Tommy Hanson | At | SRD | Francisco Liriano* | |
| September | 23 | TAM | Gavin Floyd | At | SRD | Jeremy Hellickson | |
| September | 24 | TAM | Ivan Nova | At | SRD | Paul Maholm* | |
| + Indicates In Division Game | |||||||