| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | NDF | Wade Miley* | At | EGH | Nathan Eovaldi | |
| September | 2 | NDF | Liam Hendriks | At | EGH | Jake Westbrook | |
| September | 3 | NDF | Vance Worley | At | EGH | Joe Saunders* | |
| September | 4 | VRN | Chris Sale* | At | NDF | Chris Tillman | |
| September | 5 | VRN | Yu Darvish | At | NDF | Wei-Yin Chen* | |
| September | 6 | VRN | Bronson Arroyo | At | NDF | Wade Miley* | |
| September | OFF | ||||||
| September | 7 | NDF | Liam Hendriks | At | BUR | Anibal Sanchez | |
| September | 8 | NDF | Vance Worley | At | BUR | Ryan Dempster | |
| September | 9 | NDF | Chris Tillman | At | BUR | Jordan Zimmermann | |
| September | 10 | NDF | Wei-Yin Chen* | At | GOB | Dan Haren | |
| September | 11 | NDF | Wade Miley* | At | GOB | Hiroki Kuroda | |
| September | 12 | NDF | Liam Hendriks | At | GOB | Edwin Jackson | |
| September | 13 | SYI | Travis Wood* | At | NDF | Vance Worley | |
| September | 14 | SYI | Doug Fister | At | NDF | Chris Tillman | |
| September | 15 | SYI | Clayton Richard* | At | NDF | Wei-Yin Chen* | |
| September | OFF | ||||||
| September | 16 | + | NDF | Wade Miley* | At | NIM | Justin Masterson |
| September | 17 | + | NDF | Liam Hendriks | At | NIM | Ricky Romero* |
| September | 18 | + | NDF | Vance Worley | At | NIM | Freddy Garcia |
| September | 19 | + | NDF | Chris Tillman | At | NIM | Clayton Kershaw* |
| September | 20 | + | NDF | Wei-Yin Chen* | At | NIM | Justin Masterson |
| September | 21 | + | DKZ | James McDonald | At | NDF | Wade Miley* |
| September | 22 | + | DKZ | A.J. Burnett | At | NDF | Zach McAllister |
| September | 23 | + | DKZ | Aaron Harang | At | NDF | Vance Worley |
| September | 24 | + | DKZ | Lucas Harrell | At | NDF | Cory Luebke* |
| + Indicates In Division Game | |||||||