| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | NDF | Wade Miley* | At | EGH | Nathan Eovaldi | |
| September | 2 | NDF | Liam Hendriks | At | EGH | Jake Westbrook | |
| September | 3 | NDF | Vance Worley | At | EGH | Joe Saunders* | |
| September | 4 | EGH | Matt Harrison* | At | COL | Cole Devries | |
| September | 5 | EGH | Tommy Milone* | At | COL | Cliff Lee* | |
| September | 6 | EGH | Nathan Eovaldi | At | COL | Ricky Nolasco | |
| September | OFF | ||||||
| September | 7 | + | EGH | Jake Westbrook | At | DET | Jered Weaver |
| September | 8 | + | EGH | Joe Saunders* | At | DET | Johnny Cueto |
| September | 9 | + | EGH | Matt Harrison* | At | DET | Mike Fiers |
| September | 10 | + | EGH | Tommy Milone* | At | DET | Wandy Rodriguez* |
| September | 11 | + | EGH | Nathan Eovaldi | At | DET | Homer Bailey |
| September | 12 | + | DYE | Ted Lilly* | At | EGH | Jake Westbrook |
| September | 13 | + | DYE | Felix Hernandez | At | EGH | Joe Saunders* |
| September | 14 | + | DYE | Jeff Karstens | At | EGH | Matt Harrison* |
| September | 15 | + | DYE | Bartolo Colon | At | EGH | Tommy Milone* |
| September | OFF | ||||||
| September | 16 | SRD | Mark Buehrle* | At | EGH | Nathan Eovaldi | |
| September | 17 | SRD | Francisco Liriano* | At | EGH | Jake Westbrook | |
| September | 18 | SRD | Jeremy Hellickson | At | EGH | Joe Saunders* | |
| September | 19 | EGH | Matt Harrison* | At | TAM | Ivan Nova | |
| September | 20 | EGH | Tommy Milone* | At | TAM | John Danks* | |
| September | 21 | EGH | Nathan Eovaldi | At | TAM | Luis Mendoza | |
| September | 22 | VRN | Luke Hochevar | At | EGH | Jake Westbrook | |
| September | 23 | VRN | Yu Darvish | At | EGH | Joe Saunders* | |
| September | 24 | VRN | Chris Sale* | At | EGH | Matt Harrison* | |
| + Indicates In Division Game | |||||||