| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | TAM | Ivan Nova | At | DYE | Patrick Corbin* | |
| September | 2 | TAM | Luis Mendoza | At | DYE | Felix Hernandez | |
| September | 3 | TAM | Jordan Lyles | At | DYE | Jeff Karstens | |
| September | 4 | DYE | Ted Lilly* | At | SYI | Travis Wood* | |
| September | 5 | DYE | Bartolo Colon | At | SYI | Doug Fister | |
| September | 6 | DYE | Felix Hernandez | At | SYI | Henderson Alvarez | |
| September | OFF | ||||||
| September | 7 | + | CHI | Tim Hudson | At | DYE | Patrick Corbin* |
| September | 8 | + | CHI | Matt Cain | At | DYE | Jeff Karstens |
| September | 9 | + | CHI | Kevin Millwood | At | DYE | Felix Hernandez |
| September | 10 | + | CHI | Jeff Samardzija | At | DYE | Bartolo Colon |
| September | 11 | + | CHI | Scott Feldman | At | DYE | Kris Medlen |
| September | 12 | + | DYE | Ted Lilly* | At | EGH | Jake Westbrook |
| September | 13 | + | DYE | Felix Hernandez | At | EGH | Joe Saunders* |
| September | 14 | + | DYE | Jeff Karstens | At | EGH | Matt Harrison* |
| September | 15 | + | DYE | Bartolo Colon | At | EGH | Tommy Milone* |
| September | OFF | ||||||
| September | 16 | + | DET | Jered Weaver | At | DYE | Felix Hernandez |
| September | 17 | + | DET | Johnny Cueto | At | DYE | Kris Medlen |
| September | 18 | + | DET | Mike Fiers | At | DYE | Erasmo Ramirez |
| September | 19 | + | DET | Wandy Rodriguez* | At | DYE | Ted Lilly* |
| September | 20 | + | DET | Homer Bailey | At | DYE | Felix Hernandez |
| September | 21 | + | DYE | Bartolo Colon | At | GOB | David Price* |
| September | 22 | + | DYE | Kris Medlen | At | GOB | Dan Haren |
| September | 23 | + | DYE | Jeff Karstens | At | GOB | Hiroki Kuroda |
| September | 24 | + | DYE | Erasmo Ramirez | At | GOB | Felix Doubront* |
| + Indicates In Division Game | |||||||