| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | DUB | Chris Capuano* | At | HUC | Roy Halladay | |
| September | 2 | DUB | Ross Detwiler* | At | HUC | Brandon Morrow | |
| September | 3 | DUB | Colby Lewis | At | HUC | Brandon Beachy | |
| September | 4 | NIM | Zack Greinke | At | DUB | Carlos Zambrano | |
| September | 5 | NIM | Clayton Kershaw* | At | DUB | Cole Hamels* | |
| September | 6 | NIM | Justin Masterson | At | DUB | Chris Capuano* | |
| September | OFF | ||||||
| September | 7 | + | VRN | Joe Blanton | At | DUB | Kyle Lohse |
| September | 8 | + | VRN | Chris Sale* | At | DUB | Ross Detwiler* |
| September | 9 | + | VRN | Yu Darvish | At | DUB | Carlos Zambrano |
| September | 10 | + | VRN | Bronson Arroyo | At | DUB | Cole Hamels* |
| September | 11 | + | VRN | Luke Hochevar | At | DUB | Colby Lewis |
| September | 12 | + | DUB | Chris Capuano* | At | CAL | Matt Moore* |
| September | 13 | + | DUB | Kyle Lohse | At | CAL | Josh Beckett |
| September | 14 | + | DUB | Carlos Zambrano | At | CAL | Neftali Feliz |
| September | 15 | + | DUB | Cole Hamels* | At | CAL | Mike Leake |
| September | OFF | ||||||
| September | 16 | + | DUB | Chris Capuano* | At | CRC | Mat Latos |
| September | 17 | + | DUB | Colby Lewis | At | CRC | Justin Verlander |
| September | 18 | + | DUB | Kyle Lohse | At | CRC | Stephen Strasburg |
| September | 19 | + | DUB | Carlos Zambrano | At | CRC | Josh Johnson |
| September | 20 | + | DUB | Chris Capuano* | At | CRC | Mat Latos |
| September | 21 | + | CAL | Matt Moore* | At | DUB | Cole Hamels* |
| September | 22 | + | CAL | Ervin Santana | At | DUB | Kyle Lohse |
| September | 23 | + | CAL | Tim Lincecum | At | DUB | Andrew Cashner |
| September | 24 | + | CAL | Neftali Feliz | At | DUB | Carlos Zambrano |
| + Indicates In Division Game | |||||||