| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | VRN | Brian Duensing* | At | DYE | Randy Wells | |
| September | 2 | VRN | Jonathan Sanchez* | At | DYE | Jeff Karstens | |
| September | 3 | VRN | Ervin Santana | At | DYE | Gavin Floyd | |
| September | 4 | SRD | Carlos Carrasco | At | VRN | Derek Holland* | |
| September | 5 | SRD | Daisuke Matsuzaka | At | VRN | Gio Gonzalez* | |
| September | 6 | SRD | Jeremy Hellickson | At | VRN | Brian Duensing* | |
| September | OFF | ||||||
| September | 7 | VRN | Derek Holland* | At | CVM | Chris Carpenter | |
| September | 8 | VRN | Jonathan Sanchez* | At | CVM | Brandon Morrow | |
| September | 9 | VRN | Ervin Santana | At | CVM | Carlos Villanueva | |
| September | 10 | DET | Rick Porcello | At | VRN | Brian Duensing* | |
| September | 11 | DET | Homer Bailey | At | VRN | Derek Holland* | |
| September | 12 | DET | Jered Weaver | At | VRN | Gio Gonzalez* | |
| September | 13 | VRN | Jonathan Sanchez* | At | TAM | Ted Lilly* | |
| September | 14 | VRN | Ervin Santana | At | TAM | Ryan Dempster | |
| September | 15 | VRN | Derek Holland* | At | TAM | Brandon McCarthy | |
| September | OFF | ||||||
| September | 16 | + | VRN | Brian Duensing* | At | DUB | Carlos Zambrano |
| September | 17 | + | VRN | Jonathan Sanchez* | At | DUB | Cole Hamels* |
| September | 18 | + | VRN | Derek Holland* | At | DUB | Colby Lewis |
| September | 19 | + | VRN | Ervin Santana | At | DUB | C.J. Wilson* |
| September | 20 | + | VRN | Gio Gonzalez* | At | DUB | Zach Britton* |
| September | 21 | + | BUR | Carl Pavano | At | VRN | Brian Duensing* |
| September | 22 | + | BUR | Jon Lester* | At | VRN | Derek Holland* |
| September | 23 | + | BUR | Jonathon Niese* | At | VRN | Jonathan Sanchez* |
| September | 24 | + | BUR | Anibal Sanchez | At | VRN | Ervin Santana |
| + Indicates In Division Game | |||||||