| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | TAM | Alexi Ogando | At | SRD | Jeremy Hellickson | |
| September | 2 | TAM | Tommy Hanson | At | SRD | Paul Maholm* | |
| September | 3 | TAM | Ted Lilly* | At | SRD | Alex Cobb | |
| September | 4 | DYE | Felix Hernandez | At | TAM | Brandon McCarthy | |
| September | 5 | DYE | Chris Volstad | At | TAM | Ryan Dempster | |
| September | 6 | DYE | Randy Wells | At | TAM | Alexi Ogando | |
| September | OFF | ||||||
| September | 7 | DET | Wandy Rodriguez* | At | TAM | Tommy Hanson | |
| September | 8 | DET | Jered Weaver | At | TAM | Ted Lilly* | |
| September | 9 | DET | Jaime Garcia* | At | TAM | Ryan Dempster | |
| September | 10 | TAM | Tim Stauffer | At | CVM | Javier Vazquez | |
| September | 11 | TAM | Alexi Ogando | At | CVM | Sam Lecure | |
| September | 12 | TAM | Tommy Hanson | At | CVM | Alfredo Aceves | |
| September | 13 | VRN | Jonathan Sanchez* | At | TAM | Ted Lilly* | |
| September | 14 | VRN | Ervin Santana | At | TAM | Ryan Dempster | |
| September | 15 | VRN | Derek Holland* | At | TAM | Brandon McCarthy | |
| September | OFF | ||||||
| September | 16 | + | TAM | Tommy Hanson | At | NIM | Clayton Kershaw* |
| September | 17 | + | TAM | Ted Lilly* | At | NIM | Justin Masterson |
| September | 18 | + | TAM | Ryan Dempster | At | NIM | Ubaldo Jimenez |
| September | 19 | + | TAM | Tim Stauffer | At | NIM | Roy Oswalt |
| September | 20 | + | TAM | Jeff Niemann | At | NIM | Clayton Kershaw* |
| September | 21 | + | YDR | Bruce Chen* | At | TAM | Alexi Ogando |
| September | 22 | + | YDR | Dillon Gee | At | TAM | Ted Lilly* |
| September | 23 | + | YDR | Trevor Cahill | At | TAM | Ryan Dempster |
| September | 24 | + | YDR | Brett Cecil* | At | TAM | Tim Stauffer |
| + Indicates In Division Game | |||||||