| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | COL | Madison Bumgarner* | At | NIM | Juan Nicasio | |
| September | 2 | COL | Ricky Nolasco | At | NIM | Justin Masterson | |
| September | 3 | COL | Ricky Romero* | At | NIM | Roy Oswalt | |
| September | 4 | NIM | Clayton Kershaw* | At | CHI | Jair Jurrjens | |
| September | 5 | NIM | Zack Greinke | At | CHI | Ryan Vogelsong | |
| September | 6 | NIM | Justin Masterson | At | CHI | Matt Cain | |
| September | OFF | ||||||
| September | 7 | + | NIM | Clayton Kershaw* | At | YDR | Justin Verlander |
| September | 8 | + | NIM | Scott Baker | At | YDR | Kyle Lohse |
| September | 9 | + | NIM | Justin Masterson | At | YDR | Trevor Cahill |
| September | 10 | + | NIM | Zack Greinke | At | YDR | Erik Bedard* |
| September | 11 | + | NIM | Clayton Kershaw* | At | YDR | Justin Verlander |
| September | 12 | + | DKZ | A.J. Burnett | At | NIM | Roy Oswalt |
| September | 13 | + | DKZ | Derek Lowe | At | NIM | Justin Masterson |
| September | 14 | + | DKZ | James McDonald | At | NIM | Ubaldo Jimenez |
| September | 15 | + | DKZ | Mike Pelfrey | At | NIM | Zack Greinke |
| September | OFF | ||||||
| September | 16 | + | TAM | Tommy Hanson | At | NIM | Clayton Kershaw* |
| September | 17 | + | TAM | Ted Lilly* | At | NIM | Justin Masterson |
| September | 18 | + | TAM | Ryan Dempster | At | NIM | Ubaldo Jimenez |
| September | 19 | + | TAM | Tim Stauffer | At | NIM | Roy Oswalt |
| September | 20 | + | TAM | Jeff Niemann | At | NIM | Clayton Kershaw* |
| September | 21 | + | NIM | Zack Greinke | At | DKZ | A.J. Burnett |
| September | 22 | + | NIM | Justin Masterson | At | DKZ | Derek Lowe |
| September | 23 | + | NIM | Ubaldo Jimenez | At | DKZ | James McDonald |
| September | 24 | + | NIM | Juan Nicasio | At | DKZ | Mike Pelfrey |
| + Indicates In Division Game | |||||||