| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | EGH | Matt Harrison* | At | BUR | Jonathon Niese* | |
| September | 2 | EGH | Jake Westbrook | At | BUR | Jon Lester* | |
| September | 3 | EGH | Danny Duffy* | At | BUR | Anibal Sanchez | |
| September | 4 | YDR | Trevor Cahill | At | EGH | Joe Saunders* | |
| September | 5 | YDR | Erik Bedard* | At | EGH | Fausto Carmona | |
| September | 6 | YDR | Kyle Kendrick | At | EGH | Matt Harrison* | |
| September | OFF | ||||||
| September | 7 | + | EGH | Jake Westbrook | At | CHI | Jhoulys Chacin |
| September | 8 | + | EGH | Danny Duffy* | At | CHI | Freddy Garcia |
| September | 9 | + | EGH | Joe Saunders* | At | CHI | Jair Jurrjens |
| September | 10 | + | EGH | Fausto Carmona | At | CHI | Ryan Vogelsong |
| September | 11 | + | EGH | Matt Harrison* | At | CHI | Tim Hudson |
| September | 12 | + | DYE | Gavin Floyd | At | EGH | Jake Westbrook |
| September | 13 | + | DYE | Felix Hernandez | At | EGH | J.A. Happ* |
| September | 14 | + | DYE | Chris Volstad | At | EGH | Joe Saunders* |
| September | 15 | + | DYE | Randy Wells | At | EGH | Fausto Carmona |
| September | OFF | ||||||
| September | 16 | NDF | Luke Hochevar | At | EGH | Matt Harrison* | |
| September | 17 | NDF | John Danks* | At | EGH | Danny Duffy* | |
| September | 18 | NDF | Mark Buehrle* | At | EGH | J.A. Happ* | |
| September | 19 | CAL | Jordan Zimmermann | At | EGH | Joe Saunders* | |
| September | 20 | CAL | Guillermo Moscoso | At | EGH | Fausto Carmona | |
| September | 21 | CAL | Josh Beckett | At | EGH | Matt Harrison* | |
| September | 22 | EGH | Jake Westbrook | At | SRD | Paul Maholm* | |
| September | 23 | EGH | J.A. Happ* | At | SRD | Alex Cobb | |
| September | 24 | EGH | Joe Saunders* | At | SRD | Carlos Carrasco | |
| + Indicates In Division Game | |||||||