| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | CHI | Anthony Bass | At | DUB | Colby Lewis | |
| September | 2 | CHI | Matt Cain | At | DUB | C.J. Wilson* | |
| September | 3 | CHI | Tim Hudson | At | DUB | Carlos Zambrano | |
| September | 4 | DUB | Cole Hamels* | At | COL | Jake Peavy | |
| September | 5 | DUB | Zach Britton* | At | COL | Cliff Lee* | |
| September | 6 | DUB | Colby Lewis | At | COL | Brian Sanches | |
| September | OFF | ||||||
| September | 7 | + | DUB | C.J. Wilson* | At | BUR | Jon Lester* |
| September | 8 | + | DUB | Carlos Zambrano | At | BUR | Anibal Sanchez |
| September | 9 | + | DUB | Cole Hamels* | At | BUR | Randy Wolf* |
| September | 10 | + | DUB | Colby Lewis | At | BUR | Jason Vargas* |
| September | 11 | + | DUB | C.J. Wilson* | At | BUR | Carl Pavano |
| September | 12 | + | CRC | Tim Lincecum | At | DUB | Zach Britton* |
| September | 13 | + | CRC | Shaun Marcum | At | DUB | Cole Hamels* |
| September | 14 | + | CRC | Blake Beavan | At | DUB | Colby Lewis |
| September | 15 | + | CRC | Stephen Strasburg | At | DUB | C.J. Wilson* |
| September | OFF | ||||||
| September | 16 | + | VRN | Brian Duensing* | At | DUB | Carlos Zambrano |
| September | 17 | + | VRN | Jonathan Sanchez* | At | DUB | Cole Hamels* |
| September | 18 | + | VRN | Derek Holland* | At | DUB | Colby Lewis |
| September | 19 | + | VRN | Ervin Santana | At | DUB | C.J. Wilson* |
| September | 20 | + | VRN | Gio Gonzalez* | At | DUB | Zach Britton* |
| September | 21 | + | DUB | Cole Hamels* | At | CRC | Blake Beavan |
| September | 22 | + | DUB | Colby Lewis | At | CRC | Stephen Strasburg |
| September | 23 | + | DUB | C.J. Wilson* | At | CRC | Mike Minor* |
| September | 24 | + | DUB | Chris Capuano* | At | CRC | Tim Lincecum |
| + Indicates In Division Game | |||||||