| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | CRC | Stephen Strasburg | At | GOB | Wade Davis | |
| September | 2 | CRC | Mike Minor* | At | GOB | Ivan Nova | |
| September | 3 | CRC | Mat Latos | At | GOB | Dan Haren | |
| September | 4 | HUC | Roy Halladay | At | CRC | Max Scherzer | |
| September | 5 | HUC | Ian Kennedy | At | CRC | Tim Lincecum | |
| September | 6 | HUC | Brandon Beachy | At | CRC | Shaun Marcum | |
| September | OFF | ||||||
| September | 7 | + | CAL | Daniel Hudson | At | CRC | Blake Beavan |
| September | 8 | + | CAL | Guillermo Moscoso | At | CRC | Stephen Strasburg |
| September | 9 | + | CAL | Brett Anderson* | At | CRC | Mike Minor* |
| September | 10 | + | CAL | Mike Leake | At | CRC | Mat Latos |
| September | 11 | + | CAL | Josh Beckett | At | CRC | Max Scherzer |
| September | 12 | + | CRC | Tim Lincecum | At | DUB | Zach Britton* |
| September | 13 | + | CRC | Shaun Marcum | At | DUB | Cole Hamels* |
| September | 14 | + | CRC | Blake Beavan | At | DUB | Colby Lewis |
| September | 15 | + | CRC | Stephen Strasburg | At | DUB | C.J. Wilson* |
| September | OFF | ||||||
| September | 16 | + | CRC | Mike Minor* | At | BUR | Carl Pavano |
| September | 17 | + | CRC | Mat Latos | At | BUR | Jon Lester* |
| September | 18 | + | CRC | Max Scherzer | At | BUR | Anibal Sanchez |
| September | 19 | + | CRC | Tim Lincecum | At | BUR | Randy Wolf* |
| September | 20 | + | CRC | Shaun Marcum | At | BUR | Jason Vargas* |
| September | 21 | + | DUB | Cole Hamels* | At | CRC | Blake Beavan |
| September | 22 | + | DUB | Colby Lewis | At | CRC | Stephen Strasburg |
| September | 23 | + | DUB | C.J. Wilson* | At | CRC | Mike Minor* |
| September | 24 | + | DUB | Chris Capuano* | At | CRC | Tim Lincecum |
| + Indicates In Division Game | |||||||