| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | DET | Johnny Cueto | At | CAL | Daniel Hudson | |
| September | 2 | DET | Wandy Rodriguez* | At | CAL | Josh Beckett | |
| September | 3 | DET | Jaime Garcia* | At | CAL | Guillermo Moscoso | |
| September | 4 | CAL | Dustin Moseley | At | SSB | Kevin Correia | |
| September | 5 | CAL | Brett Anderson* | At | SSB | Jeremy Guthrie | |
| September | 6 | CAL | Mike Leake | At | SSB | Doug Fister | |
| September | OFF | ||||||
| September | 7 | + | CAL | Daniel Hudson | At | CRC | Blake Beavan |
| September | 8 | + | CAL | Guillermo Moscoso | At | CRC | Stephen Strasburg |
| September | 9 | + | CAL | Brett Anderson* | At | CRC | Mike Minor* |
| September | 10 | + | CAL | Mike Leake | At | CRC | Mat Latos |
| September | 11 | + | CAL | Josh Beckett | At | CRC | Max Scherzer |
| September | 12 | + | BUR | Jon Lester* | At | CAL | Jordan Zimmermann |
| September | 13 | + | BUR | Jonathon Niese* | At | CAL | Dustin Moseley |
| September | 14 | + | BUR | Randy Wolf* | At | CAL | Brett Anderson* |
| September | 15 | + | BUR | Jason Vargas* | At | CAL | Guillermo Moscoso |
| September | OFF | ||||||
| September | 16 | SRD | Jeremy Hellickson | At | CAL | Josh Beckett | |
| September | 17 | SRD | Paul Maholm* | At | CAL | Dustin Moseley | |
| September | 18 | SRD | Alex Cobb | At | CAL | Daniel Hudson | |
| September | 19 | CAL | Jordan Zimmermann | At | EGH | Joe Saunders* | |
| September | 20 | CAL | Guillermo Moscoso | At | EGH | Fausto Carmona | |
| September | 21 | CAL | Josh Beckett | At | EGH | Matt Harrison* | |
| September | 22 | NDF | John Danks* | At | CAL | Mike Leake | |
| September | 23 | NDF | Mark Buehrle* | At | CAL | Daniel Hudson | |
| September | 24 | NDF | Michael Pineda | At | CAL | Jordan Zimmermann | |
| + Indicates In Division Game | |||||||