| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| September | 1 | EGH | Matt Harrison* | At | BUR | Jonathon Niese* | |
| September | 2 | EGH | Jake Westbrook | At | BUR | Jon Lester* | |
| September | 3 | EGH | Danny Duffy* | At | BUR | Anibal Sanchez | |
| September | 4 | BUR | Randy Wolf* | At | CVM | Javier Vazquez | |
| September | 5 | BUR | Jason Vargas* | At | CVM | C.C. Sabathia* | |
| September | 6 | BUR | Carl Pavano | At | CVM | Sam Lecure | |
| September | OFF | ||||||
| September | 7 | + | DUB | C.J. Wilson* | At | BUR | Jon Lester* |
| September | 8 | + | DUB | Carlos Zambrano | At | BUR | Anibal Sanchez |
| September | 9 | + | DUB | Cole Hamels* | At | BUR | Randy Wolf* |
| September | 10 | + | DUB | Colby Lewis | At | BUR | Jason Vargas* |
| September | 11 | + | DUB | C.J. Wilson* | At | BUR | Carl Pavano |
| September | 12 | + | BUR | Jon Lester* | At | CAL | Jordan Zimmermann |
| September | 13 | + | BUR | Jonathon Niese* | At | CAL | Dustin Moseley |
| September | 14 | + | BUR | Randy Wolf* | At | CAL | Brett Anderson* |
| September | 15 | + | BUR | Jason Vargas* | At | CAL | Guillermo Moscoso |
| September | OFF | ||||||
| September | 16 | + | CRC | Mike Minor* | At | BUR | Carl Pavano |
| September | 17 | + | CRC | Mat Latos | At | BUR | Jon Lester* |
| September | 18 | + | CRC | Max Scherzer | At | BUR | Anibal Sanchez |
| September | 19 | + | CRC | Tim Lincecum | At | BUR | Randy Wolf* |
| September | 20 | + | CRC | Shaun Marcum | At | BUR | Jason Vargas* |
| September | 21 | + | BUR | Carl Pavano | At | VRN | Brian Duensing* |
| September | 22 | + | BUR | Jon Lester* | At | VRN | Derek Holland* |
| September | 23 | + | BUR | Jonathon Niese* | At | VRN | Jonathan Sanchez* |
| September | 24 | + | BUR | Anibal Sanchez | At | VRN | Ervin Santana |
| + Indicates In Division Game | |||||||