| Month | Game | + | Away | Pitcher | At | Home | Pitcher |
| August | 1 | NIM | Justin Masterson | At | DET | Jaime Garcia* | |
| August | 2 | NIM | Clayton Kershaw* | At | DET | Wandy Rodriguez* | |
| August | 3 | NIM | Zack Greinke | At | DET | Rick Porcello | |
| August | 4 | CRC | Shaun Marcum | At | NIM | Ubaldo Jimenez | |
| August | 5 | CRC | Mat Latos | At | NIM | Roy Oswalt | |
| August | 6 | CRC | Max Scherzer | At | NIM | Clayton Kershaw* | |
| August | OFF | ||||||
| August | 7 | + | YDR | Trevor Cahill | At | NIM | Justin Masterson |
| August | 8 | + | YDR | Erik Bedard* | At | NIM | Zack Greinke |
| August | 9 | + | YDR | Justin Verlander | At | NIM | Clayton Kershaw* |
| August | 10 | + | YDR | Kyle Lohse | At | NIM | Ubaldo Jimenez |
| August | 11 | + | YDR | Bruce Chen* | At | NIM | Justin Masterson |
| August | 12 | + | NIM | Roy Oswalt | At | NDF | Matt Garza |
| August | 13 | + | NIM | Clayton Kershaw* | At | NDF | Kyle McClellan |
| August | 14 | + | NIM | Zack Greinke | At | NDF | Luke Hochevar |
| August | 15 | + | NIM | Justin Masterson | At | NDF | Michael Pineda |
| August | OFF | ||||||
| August | 16 | + | NIM | Clayton Kershaw* | At | TAM | Brandon McCarthy |
| August | 17 | + | NIM | Ubaldo Jimenez | At | TAM | Tim Stauffer |
| August | 18 | + | NIM | Justin Masterson | At | TAM | Jeff Niemann |
| August | 19 | + | NIM | Roy Oswalt | At | TAM | Ryan Dempster |
| August | 20 | + | NIM | Clayton Kershaw* | At | TAM | Ted Lilly* |
| August | 21 | + | NDF | John Danks* | At | NIM | Zack Greinke |
| August | 22 | + | NDF | Matt Garza | At | NIM | Justin Masterson |
| August | 23 | + | NDF | Kyle McClellan | At | NIM | Ubaldo Jimenez |
| August | 24 | + | NDF | Luke Hochevar | At | NIM | Clayton Kershaw* |
| + Indicates In Division Game | |||||||